別 名: lysyl-tRNA synthetase 1; KRS; KARS; KARS2; CMTRIB; DFNB89
概 述
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Full name: |
lysyl-tRNA synthetase 1 |
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Synonyms: |
KRS; KARS; KARS2; CMTRIB; DFNB89 |
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Swissprot: |
Q15046 |
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Gene Accession: |
BC004132 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
