英文名稱(chēng)： AKR1D1 Antigen (Recombinant Protein)
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Full name: |
aldo-keto reductase family 1, member D1 |
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Synonyms: |
CBAS2; SRD5B1; 3o5bred |
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Swissprot: |
P51857 |
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Gene Accession: |
BC130625 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. |
